Biosonics

Biosonics is building a new class of biomolecular imaging tools that make it possible to visualise cellular activity deep inside living tissue—non-invasively and in real time. Their technology, NSSM, leverages acoustic reporter genes (ARGs): genetically encoded proteins that produce ultrasound contrast when expressed in cells.

This innovation allows researchers to observe living cells in 3D with fine spatial detail (100 μm resolution), going far beyond the depth limitations of optical microscopy—without biopsies, phototoxicity or extensive sample prep. The result: dynamic, quantitative insights into cellular processes as they unfold in vivo.

Biosonics’ platform is still in development but has the potential to transform molecular imaging for both basic biology and cell therapy R&D. Their future business model is based on providing research institutes and biotech companies with integrated hardware and software systems for acquisition and analysis.